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Index > Protein center > Lyve1(Gene name) > Mouse
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  • Lyve1 (Gene name),
  • Lymphatic vessel endothelial hyaluronic acid receptor 1 (Protein name ),  LYVE1_MOUSE from NCBI database.
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  • Gene name:
    Lyve1(Crsbp1;Xlkd1);
    Protein name:
    Lymphatic vessel endothelial hyaluronic acid receptor 1(LYVE-1);
    Alternative:
    Extracellular link domain-containing protein 1;Cell surface retention sequence-binding protein 1(CRSBP-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with PDGFB and IGFBP3. Forms a transient ternary complex with PDGFB and PDGFRB in TGN.
    Function:
    Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
    Subcellular Location:
    Membrane Single-pass type I membrane protein Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
    Protein Attributes:
    Sequence length:
    318
    Sequence:
    50:
    MLQHTSLVLL | LASIWTTRHP | VQGADLVQDL | SISTCRIMGV | ALVGRNKNPQ | 
    100:
    MNFTEANEAC | KMLGLTLASR | DQVESAQKSG | FETCSYGWVG | EQFSVIPRIF | 
    150:
    SNPRCGKNGK | GVLIWNAPSS | QKFKAYCHNS | SDTWVNSCIP | EIVTTFYPVL | 
    200:
    DTQTPATEFS | VSSSAYLASS | PDSTTPVSAT | TRAPPLTSMA | RKTKKICITE | 
    250:
    VYTEPITMAT | ETEAFVASGA | AFKNEAAGFG | GVPTALLVLA | LLFFGAAAVL | 
    300:
    AVCYVKRYVK | AFPFTTKNQQ | KEMIETKVVK | EEKADDVNAN | EESKKTIKNP | 
    318:
    EEAKSPPKTT | VRCLEAEV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse LYVE-1
    Cat.:
    E13600m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse LYVE-1
    Cat.:
    E13600h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse LYVE-1
    Cat.:
    E13600b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse LYVE-1
    Cat.:
    U13600m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LYVE-1
    Cat.:
    U13600h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LYVE-1
    Cat.:
    U13600b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse LYVE-1
    Cat.:
    P13600Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse LYVE-1
    Cat.:
    P13600Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse LYVE-1
    Monoclonal Antibody for Mouse LYVE-1
    Monoclonal Antibody for Mouse LYVE-1
    Monoclonal Antibody for Mouse LYVE-1
    Protein for Mouse LYVE-1
    Protein for Mouse LYVE-1
    Protein for Mouse LYVE-1

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    References
    1. 1.
      "LYVE-1, a new homologue of the CD44 glycoprotein is a lymph-specific receptor for hyaluronan."
      Banerji S. , Ni J. , Wang S.-X. , Clasper S. , Su J. , Tammi R. , Jones M. , Jackson D.G.
      J. Cell Biol.144:789-801(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Gastrointestinal tract.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Brain.
      tissue: Lung.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      tissue: Lung.
      tissue: Mammary gland.
    4. 4.
      "Cell surface retention sequence binding protein-1 interacts with the v-sis gene product and platelet-derived growth factor beta-type receptor in simian sarcoma virus-transformed cells."
      Boensch C. , Huang S.S. , Connolly D.T. , Huang J.S.
      J. Biol. Chem.274:10582-10589(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PDGFB;SUBCELLULAR LOCATION
    5. 5.
      "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides."
      Bernhard O.K. , Kapp E.A. , Simpson R.J.
      J. Proteome Res.6:987-995(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-52
      strain: C57BL/6.
      tissue: Plasma.
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